Tc-99m-MIBI is a substrate for ATP-binding cassette (ABC) transporter proteins, including P-glycoprotein (P-gp), and has been used to image their expression, mainly in cancer. Imaging P-gp expression may have a role in renal transplantation and investigating drug toxicity. The aim of the project was to develop a functional imaging assay for ABC-transporters using Tc-99m-MIBI.
|Date of Award||Mar 2015|
Imaging physiological ABC transporter expression and its relation to disease using Tc-99m-hexakis-methoxy-isobutyl isonitrile (Tc-99m-MIBI)
Dizdarevic, S. (Author). Mar 2015
Student thesis: Doctoral Thesis